Research & Initiatives

The research of my lab aims to unravel the molecular and cellular mechanisms of liver cancer. The current research of my lab focuses on the integrated functional genomics of liver cancer using genome-scale technologies coupled with clinical translational studies. I have an active program in the basic/translational research of liver cancer, using state-of-the art molecular approaches including genomics, transcriptomics, and single cell analysis, to capture cancer heterogeneity, identify novel subclones, and unravel signaling pathways. I am coupling genomics, genetics, functional molecular analysis and in vivo pre-clinical animal models as well as patient-derived tumor xenograft models to address the molecular mechanisms of this cancer. We work towards translational application for early detection, diagnosis, prognosis and patient stratification towards precision oncology.